• Bin Peng
    • Professor
    • Phone No:
    • E-mail: phs301@vip.163.com

    Departments

    Research Field

    Pulp Biology and Endodontics

    Education

             · Ph.D. candidate, from July 1991 to July 1994, Supervised by Prof. Fan Mingwen

     

    • Postgraduate student for a Master’s degree, from July 1985 to June 1988

     

    • Undergraduate student, from September 1978 to July 1982

     

    Oversea Study and Visit

     

    • August, 2002 - February, 2003: University of Copenhagen, Denmark; Cooperative Researcher
    • 1996 - 1997: School of Dentistry, University of Copenhagen, Denmark; Cooperative Researcher

     

    Honors and Awards

     

        ·National Nature Science Foundation of China. Negative regulation of S1P/S1P1 signaling axis on Treg cells in periapical bone destruction. 81070823

     

    ·National Nature Science Foundation of China. Regulation of Wnt/β-catenin on tolDC and periapical bone

     destruction. 81170956

     

    ·National Nature Science Foundation of China. Neutrophil extracellular traps (NETs) driven by autophagy and periapical bone destruction. 81371131

     

    ·National Nature Science Foundation of China. exFoxp3 Th17 driven by JAK2/STAT3 and periapical bone destruction. 81570973

    Publications

     

    1. Zhang C, Yang L, Peng B*. Critical role of NFATc1 in periapical lesions. Int Endod J, 2010, 43(2):109-14

     

    2. Xiong H,Wei L, Hu Y, Zhang C, Peng B*. Effect of alendronate on alveolar bone resorption and angiogenesis in rats with experimental periapical lesions. Int Endod J, 2010, 43(6):485-91

     

    3.Zhang W, Li Z, Peng B*. Ex vivo cytotoxicity of a new calcium silicate-based canal filling material. Int Endod J, 2010, 43(9):769-74.

     

    4.Yuan Z, Peng B, Jiang H*. Effect of bioaggregate on mineral- associated gene expression in osteoblast cells. J Endod, 2010, 36(7):1145-8.

     

    5.Yan P, Yuan Z, Jiang H, Peng B*. Effect of bioaggregate on differenti ation of human periodontal ligament fibroblasts. Int Endod J, 2010, 43(12):1116-21

     

    6.Zhang W,Li Z,Peng B*. Effects of iRoot SP on Mineralization-related Genes Expression in MG63 Cells. J Endod, 2010, 36(12):1978-82.

    7.Wang L,Zhang R,Xiong H,Peng B*. The involvement of Platelet-derived growth factor-A in the course of apical periodontitis. Int Endod J, 2011, 44(1):65-71

     

    8.Zhu L,Wu Y,Wei H,Xing X,Zhan N,Xiong H,Peng B*. IL-17R activation of human periodontal ligament fibroblasts induces IL-23 p19 production:Differential involvement of NF-κB versus JNK/AP- 1pathways. Mol Immunol, 2011, 48(4):647-56

     

    9. Zhu X, Huang C, Peng B*. Overexpression of thioredoxin system proteins predicts poor prognosis in patients with squamous cell carcinoma of the tongue. Oral Oncol, 2011, 47(7):609-14

     

    10.Liu L, Zhang C, Hu Y,  Peng B*. Protective effect of metformin on periapical lesions in rats by decreasing the ratio of receptor activator of nuclear factor kappa B ligand/osteoprotegerin. J Endod, 2012, 38(7):943-7.

     

    11.Zhu L, Wei H, Wu Y, Yang S, Xiao L, Zhang J, Peng B*. Licorice isoliquiritigenin suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. Int J Biochem Cell Biol, 2012, 44(7):1139-52.

     

    12. Zhu L, Wu Y, Wei H, Yang S, Zhan N, Xing X, Peng B*. Up-regulation of IL-23 p19 expression in human periodontal ligament fibroblasts by IL-1β via concurrent activation of the NF-κB and MAPKs/AP-1 pathways. Cytokine, 2012, 60(1):171-8.

     

    13. Wu Y, Zhu L, Wei H, Peng B*. Regulation of matrix metalloproteinases, tissue inhibitor of matrix metalloproteinase-1, and extracellular metalloproteinase inducer by interleukin-17 in human periodontal ligament fibroblasts. J Endod. 2013 Jan; 39(1):62-7.

     

    14. Zhao D, Shen Y, Peng B, Haapasalo M. Micro-computed tomography evaluation of the preparation of mesiobuccal root canals in maxillary first molars with Hyflex CM, Twisted Files, and K3 instruments. J Endod 2013; 39(3):385-8.

     

    15. Hu Y, Xiong H, Peng B*. Expression of a cytokine, interleukin-23, in experimental periapical lesions. Int Endod J 2013; 46(10):896-903.

     

    16. Liu L, Peng B*. The expression of macrophage migration inhibitory factor is correlated with receptor activator of nuclear factor kappa B ligand in induced rat periapical lesions. J Endod 2013; 39(8):984-9.

     

    17. Zhu L, Yang J, Zhang J, Peng B*. The presence of autophagy in human periapical lesions. J Endod 2013; 39(11):1379-84.

     

    18. Li Z, He M, Peng B, Jin Z. Strontium concentrations and isotope ratios in enamel of healthy and carious teeth in southern Shaanxi, China.Rapid Commun Mass Spectrom. 2013;27(17):1919-24.

     

    19. Wang L, Sun Z, Liu L, Peng B*. Expression of CX3CL1 and its receptor, CX3CR1, in the development of periapical lesions. Int Endod J 2014; 47(3):271-9.

     

    20. Wu Y, Zhu L, Liu L, Zhang J, Peng B*. Interleukin-17A stimulates migration of periodontal ligament fibroblasts via p38 MAPK/NF-κB -dependent MMP-1 expression. J Cell Physiol 2014; 229(3):292-9.

     

    21. Yang S, Zhu L, Xiao L, Shen Y, Wang L, Peng B, Haapasalo M. Imbalance of interleukin-17+ T-cell and Foxp3+ regulatory T-cell dynamics in rat periapical lesions. J Endod 2014; 40(1):56-62.

     

    22. Sun Z, Wang L, Peng B*. Kinetics of glycogen synthase kinase (GSK)3β and phosphorylated GSK3β (Ser 9) expression in experimentally induced periapical lesions. Int Endod J 2014; 47(12):1107-16.

     

    23. Liu L, Wang L, Wu Y, Peng B*. The expression of MCP-1 and CCR2 in induced rats periapical lesions. Arch Oral Biol 2014; 59(5):492-9.

     

    24. Zhao D, Shen Y, Peng B, Haapasalo M. Root canal preparation of mandibular molars with 3 nickel-titanium rotary instruments: a micro-computed tomographic study. J Endod 2014; 40(11):1860-4.

     

    25. Zhu L, Yang J, Zhang J, Lei D, Xiao L, Cheng X, Lin Y, Peng B*. In vitro and in vivo evaluation of a nanoparticulate bioceramic paste for dental pulp repair. Acta Biomater 2014; 10(12):5156-68.

     

    26. Zhang R, Huang S, Wang L, Peng B*. Histochemical localization of Dickkopf-1 in induced rat periapical lesions. J Endod 2014; 40(9):1394-9.

     

    27. Zhu L, Yang J, Zhang J, Peng B*. A comparative study of BioAggregate and ProRoot MTA on adhesion, migration, and attachment of human dental pulp cells. J Endod 2014; 40(8):1118-23.

     

    28. Xiong H, Wei L, Peng B*. IL-17 stimulates the production of the inflammatory chemokines IL-6 and IL-8 in human dental pulp fibroblasts. Int Endod J 2015; 48(6):505-11.

     29. Ma JZ, Shen Y, Al-Ashaw AJ, Khaleel HY, Yang Y, Wang ZJ, Peng B, Haapasalo M. Micro-computed tomography evaluation of the removal of calcium hydroxide medicament from C-shaped root canals of mandibular second molars. Int Endod J 2015; 48(4):333-41.

     

    30. Zhang J, Zhu L, Yan P, Peng B*. Effect of BioAggregate on Receptor Activator of Nuclear Factor-Kappa B Ligand-induced Osteoclastogenesis from Murine Macrophage Cell Line In Vitro. J Endod 2015; 41(8):1265-71.

     

    31. Zhang J, Zhu LX, Cheng X, Lin Y, Yan P, Peng B*. Promotion of Dental Pulp Cell Migration and Pulp Repair by a Bioceramic Putty Involving FGFR-mediated Signaling Pathways. J Dent Res 2015; 94(6):853-62.

     

    32. Xiao L, Zhu L, Yang S, Lei D, Xiao Y, Peng B*. Different correlation of sphingosine-1-phosphate receptor 1 with receptor activator of nuclear factor kappa B ligand and regulatory T cells in rat periapical lesions. J Endod 2015; 41(4):479-86.

     

    33. Zhang J, Zhu L, Peng B*. Effect of BioAggregate on osteoclast differentiation and inflammatory bone resorption in vivo. Int Endod 2015; 48(11):1077-85.

     

    34. Zhu LX, Zhang J, Xiao L, Liu S, Yu JJ, Chen WH, Zhang XZ, Peng B*. Autophagy in resin monomer-initiated toxicity of dental mesenchymal cells: a novel therapeutic target of N-acetyl cysteine. Journal of materials chemistry B. 2015; 3(33): 6820-36.

     

    35. Zhang W, Peng B*. Tissue reactions after subcutaneous and intraosseous implantation of iRoot SP, MTA and AH Plus. Dent Mater J. 2015;34(6):774-80.

     

    36. Zhao D, Shen Y, Peng B, Haapasalo M. Effect of autoclave sterilization on the cyclic fatigue resistance of thermally treated Nickel-Titanium instruments. Int Endod J 2016; 49(10):990-5.

     

    37. Liu S, Zhu L, Zhang J, Yu J, Cheng X, Peng B*. Anti-osteoclastogenic activity of isoliquiritigenin via inhibition of NF-κB-dependent autophagic pathway.Biochem Pharmacol. 2016;106:82-93.

     

    38. Zhao D, Shen Y, Peng B*, Haapasalo M*. Effect of autoclave sterilization on the cyclic fatigue resistance of thermally treated Nickel-Titanium instruments. Int Endod J. 2016;49(10):990-5.

     

    39. Lv F, Zhu L, Zhang J, Yu J, Cheng X, Peng B*. Evaluation of the in vitro biocompatibility of a new fast-setting ready-to-use root filling and repair material. Int Endod J. 2017;50(6):540-548.

     

    40. Yu JJ, Zhu LX, Zhang J, Liu S, Lv FY, Cheng X, Liu GJ, Peng B*. From the Cover: Activation of NF-κB-Autophagy Axis by 2-Hydroxyethyl Methacrylate Commits Dental Mesenchymal Cells to Apoptosis. Toxicol Sci. 2017;157(1):100-111.