• Bin Shi
    • Professor
    • Phone No: 027-87686600
    • E-mail: shibin_dentist@whu.edu.cn


    Research Field

    ·Prevention and treatment of peri-implantitis

    ·stem cells and bone regeneration

    ·New bio-materials for bone regeneration


    ·  Ph.D. candidate, from Sep 2002 to July 2005, Majored in oral prosthodontics, Supervised by Prof. Xiangrong Cheng

    ·  Postgraduate student for a Master’s degree, from Sep 1990 to July 1993, majored in oral prosthodontics, Supervised by Prof. Xiangrong Cheng

    ·  Undergraduate student, from September 1979 to July 1984


    Oversea Study and Visit

    ·May, 1998 - May, 1999  Canadian dental implant Research Institute. Visiting Scholar 

    Honors and Awards

    ·National Nature Science Foundation of China. Construction of peri-implant periodontal ligament with multipotent stem cells derived from iPS. 81170992


    1. The impact of Wnt signalling and hypoxia on osteogenic and cementogenic differentiation in human periodontal ligament cells. Li S, Shao J, Zhou Y, Friis T, Yao J, Shi B, Xiao Y. Mol Med Rep. 2016 Dec;14(6):4975-4982.
    2. Caffeic acid phenethyl ester attenuates lipopolysaccharide-stimulated proinflammatory responses in human gingival fibroblasts via NF-κB and PI3K/Akt signaling pathway. Li L, Sun W, Wu T, Lu R, Shi B.Eur J Pharmacol. 2017 Jan 5;794:61-68.
    3. The effect of mesoporous bioglass on osteogenesis and adipogenesis of osteoporotic BMSCs. Wu T, Cheng N, Xu C, Sun W, Yu C, Shi B. J Biomed Mater Res A. 2016 Dec;104(12):3004-3014
    4. Water-soluble photoluminescent fullerene capped mesoporous silica for pH-responsive drug delivery and bioimaging. Tan L, Wu T, Tang ZW, Xiao JY, Zhuo RX, Shi B, Liu CJ. Nanotechnology. 2016 Jun 27;27(31):315104.
    5. Bone scaffolds loaded with siRNA-Semaphorin4d for the treatment of osteoporosis related bone defects. Zhang Y, Wei L, Miron RJ, Shi B, Bian Z.Sci Rep. 2016 Jun 2;6:26925.
    6. PNIPAAM modified mesoporous hydroxyapatite for sustained osteogenic drug release and promoting cell attachment. Wu T, Tan L, Cheng N, Yan Q, Zhang YF, Liu CJ, Shi B. Mater Sci Eng C Mater Biol Appl. 2016 May;62:888-96.
    7. Augmentation of the alveolar ridge compared with shorter implants in atrophic jaws: a meta-analysis based on randomised controlled trials.Yang J, Cheng Z, Shi B. Br J Oral Maxillofac Surg. 2016 Jan;54(1):68-73.
    8. The Expression and Correlation of iNOS and p53 in Oral Squamous Cell Carcinoma. Yang L, Wang Y, Guo L, Wang L, Chen W, Shi B. Biomed Res Int. 2015;2015:637853.
    9. Controlled release of simvastatin-loaded thermo-sensitive PLGA-PEG-PLGA hydrogel for bone tissue regeneration: in vitro and in vivo characteristics. Yan Q, Xiao LQ, Tan L, Sun W, Wu T, Chen LW, Mei Y, Shi B. J Biomed Mater Res A. 2015 Nov;103(11):3580-9.
    10. Effect of retinoic acid on the function of lipopolysaccharide-stimulated bone marrow stromal cells grown on titanium surfaces. Yan Q, Li Y, Cheng N, Sun W, Shi B. Inflamm Res. 2015 Jan;64(1):63-70
    11. Effects of Er-Zhi-Wan on microarchitecture and regulation of Wnt/β-catenin signaling pathway in alveolar bone of ovariectomized rats. Sun W, Wang YQ, Yan Q, Lu R, Shi B. J Huazhong Univ Sci Technolog Med Sci. 2014 Feb;34(1):114-9.
    12. The osteogenic potential of mesoporous bioglasses/silk and non-mesoporous bioglasses/silk scaffolds in ovariectomized rats: in vitro and in vivo evaluation. Cheng N, Wang Y, Zhang Y, Shi B. PLoS One. 2013 Nov 12;8(11):e81014.
    13. Porous CaP/silk composite scaffolds to repair femur defects in an osteoporotic model. Cheng N, Dai J, Cheng X, Li S, Miron RJ, Wu T, Chen W, Zhang Y, Shi B. J Mater Sci Mater Med. 2013 Aug;24(8):1963-75.
    14. Effect of decreased implant healing time on bone (re)modeling adjacent to plateaued implants under functional loading in a dog model. Dai J, Cheng N, Miron RJ, Shi B, Cheng X, Zhang Y. Clin Oral Investig. 2014 Jan;18(1):77-86.
    15. Effects of erythropoietin on osteoblast proliferation and function. Guo L, Luo T, Fang Y, Yang L, Wang L, Liu J, Shi B*. Clin Exp Med. 2012 Nov 8.
    16. Zhang Y, Cheng N, Miron R, Shi B, Cheng X. Delivery of PDGF-B and BMP-7 by mesoporous bioglass/silk fibrin scaffolds for the repair of osteoporotic defects. Biomaterials. 2012 Oct;33(28):6698-708.
    17. Luo T, Zhang W, Shi B, Cheng X, Zhang Y. Enhanced bone regeneration around dental implant with bone morphogenetic protein 2 gene and vascular endothelial growth factor protein delivery. Clin Oral Implants Res. 2012 Apr;23(4):467-73.
    18. Sun HL, Huang C, Wu YR, Shi B. Failure rates of short (≤ 10 mm) dental implants and factors influencing their failure: a systematic review. Int J Oral Maxillofac Implants. 2011 Jul-Aug;26(4):816-25. Review.
    19. Liao F, Chen Y, Li Z, Wang Y, Shi B, Gong Z, Cheng X. A novel bioactive three-dimensional beta-tricalcium phosphate/chitosan scaffold for periodontal tissue engineering. J Mater Sci Mater Med. 2010 Feb;21(2):489-96.